What is rheumatoid arthritis?

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Rheumatoid Arthritis

Rheumatoid arthritis is an often chronic systemic disease that causes inflammatory changes in the synovium, or joint lining, that result in pain, stiffness, swelling, and loss of function in the joints. The disease can also affect other parts of the body.

It is an automimmune disease. It is characterized by an increase in TNF-alpha, IL-6 and other inflammatory mediators. Depending on the severity it can be treated with NSAIDS, immune system depressents or anti-TNF-alpha drugs.

First answer by anonymous. Last edit by ID2494628309. Question popularity: 159 [recommend question]

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